RETSCH MM 400 Mixer Mill

RETSCH MM 400 Mixer Mill – Fast, Efficient Grinding & Homogenizing

The RETSCH 207150001 Mixer Mill MM 400 is a compact bench-top unit for a wide range of grinding applications. Whether you need to dry, wet or cryogenic grind small sample amounts, this mixer mill can do it all. In just a few seconds it mixes and homogenizes powders and suspensions, perfect for various applications. For those seeking precise mixing and homogenizing, the RETSCH Mortar Grinder RM 200 offers an efficient solution, ideal for materials requiring high viscosity operation.

Not only can it grind and mix different materials but also disrupt biological cells and process biological samples, extract DNA/RNA and proteins. High performance and flexibility makes it a unique product in the market, you get the functionality you need for your lab or research, such as with our Soil Grinder 220V.

Accessories like transparent pmma grinding jars and balls need to be ordered separately as they are not included with the mixer mill. But they are available to buy.

If you need a mill with high input you might also want to look into the planetary Ball Mill Emax. This mill introduces a completely new type of grinding, high friction and impact to get extreme fine particles in no time.

The function principle of the Mixer Mill MM 400 is the grinding jars oscillate radially in horizontal position. The inertia of the grinding balls makes them impact with energy on the sample material and pulverize it. The movement of the grinding jars and the balls also ensures intense sample mixing. The degree of mixing can be increased by using smaller balls, especially for disrupting biological cells.

Mixer Mill MM 400 can be used for various applications like grinding and homogenization of alloys, animal feed, bones, ceramics, cereals, chemicals, electronic scrap, glass, grains, hair, minerals, oil seeds, ores, paper, plant materials, plastics, sewage sludge, soils, straw, tablets, textiles, tissue, tobacco, waste samples, wood, wool and more.

With reproducible and efficient grinding, mixing and homogenization the Mixer Mill MM 400 saves you time and effort in your lab work. Powerful grinding through impact and friction, dry, wet or cryogenic grinding mode. Screw-top grinding jars leak-proof grinding and up to 9 standard operating procedures (SOPs) can be stored.

To increase its functionality the Mixer Mill MM 400 is compatible with a wide range of accessories like different jar and ball sizes, adapter racks for single-use vials and tubes, various grinding tool materials and the CryoKit. It also disrupts up to 240 ml cell suspension for DNA/RNA and protein extraction.

For more information see product manual.

RETSCH 207450001 Mixer mill MM 400 is a compact bench-top unit, developed for dry, wet and cryogenic grinding of small sample amounts. It mixes and homogenizes powders and suspensions in a few seconds. Also suitable for disruption of biological cells and DNA/RNA and protein extraction. High performance and flexibility, unique product in the market. Accessories not included.

Accessories like grinding jars and balls need to be ordered separately.

You might also want to look into the grinding Ball Mill Emax, a completely new type of mill for input. The unique combination of high friction and impact gets extreme fine particles in no time.

Introduction to the Instrument

The Mixer Mill MM 400 is a true multipurpose mill designed for dry, wet, and cryogenic grinding of small volumes up to 2 x 20 ml. This compact benchtop unit provides substantially higher performance compared to other mixer mill models, making it an indispensable tool for laboratories and testing labs. Operating on the same functional principle as the MM 500 nano and MM 500 vario, the MM 400 offers a more compact design with higher energy input. This instrument is ideal for a wide range of applications, including classic homogenization processes, biological cell disruption, and cryogenic grinding. With its user-friendly interface and easily accessible components, the MM 400 ensures efficient and effective sample processing.

Overview and Features

RETSCH MM 400 Mixer mill is a versatile and powerful lab tool for dry, wet and cryogenic grinding of small sample amounts. With its compact bench-top design the Mixer Mill MM 400 is perfect for mixing and homogenizing powders and suspensions in a few seconds. The mill has 2 grinding stations to prepare up to 20 samples at the same time. High-performance grinding for size reduction at each grinding station, mixing, homogenization, cell disruption and cryogenic grinding. The RETSCH ZM 300 Ultra Centrifugal Mill offers alternative high-performance capabilities with a focus on soft to medium-hard materials. The MM 500 nano and MM 500 vario models operate at a frequency of 35 Hz and provide higher performance compared to the MM 400. The MM 400 was designed with extensive input from professionals, ensuring practical and useful features for real-world applications.

Function Principle

The grinding jars of the Mixer Mill MM 400 perform radial oscillations in a horizontal position. The inertia of the grinding balls hits the sample material at the rounded ends of the grinding jars with high energy and pulverizes it. The high-energy impacts from the grinding balls result in effective pulverization and mixing of the sample material. The movement of the grinding jars combined with the movement of the balls mixes the sample. The degree of mixing can be increased by using several smaller balls. If several small balls (e.g. glass beads) are used then, for example, biological cells can be disrupted. The large frictional impact between the beads disrupts the cells.

Sample Material, Grinding Modes, and Cryogenic Grinding

The Mixer Mill MM 400 can process various sample materials like tablets, minerals, bones, tissues, soils and plastics. Adapting the jar size to the sample volume is crucial for optimal grinding results. It can be used for dry grinding, wet grinding and cryogenic grinding. The grinding jars are available in different sizes and materials (stainless steel, tungsten carbide, glass) to accommodate different sample types and grinding modes. The balls are designed for effective cell disruption and intensive mixing, perfect for biological cell disruption and protein extraction.

Cryogenic Grinding

Cryogenic grinding is a process that involves grinding samples at extremely low temperatures, making it ideal for materials that are sensitive to heat or require specific temperature conditions for optimal grinding. The Mixer Mill MM 400 is perfectly suited for cryogenic grinding of small volumes up to 2 x 20 ml. It can be used with various grinding tool materials, such as tungsten carbide, zirconium oxide, and stainless steel, to ensure efficient grinding and minimize contamination. This process is particularly useful for applications like protein extraction, cell disruption and sample preparation for analytical techniques, providing precise and reliable results.

Technical Data

• Power supply: 100-240V, 50/60Hz

• Final fineness: up to 5 µm

• Grinding method: Impact and friction grinding

• Frequency: up to 30 Hz

• Application: Dry, wet and cryogenic grinding of small sample amounts

• Usage: Mixing and homogenizing powders, disruption of cells in cell suspension, extraction of DNA/RNA and proteins, isolation of tissue bacteria tubes

• Accurate diagnosis: Efficiently isolates intact bacteria from tissue samples, enabling effective DNA/RNA and protein extraction for reliable diagnostic outcomes

• Grinding jars: 1.5 ml to 50 ml in 6 different grinding tool materials

• Grinding balls: different sizes and grinding tool materials, stainless steel, tungsten carbide, glass

Accessories and Consumables

The Mixer Mill MM 400 can be equipped with a variety of accessories and consumables to enhance its functionality and versatility. These include screw-top grinding jars made from different materials, such as stainless steel, agate, and tungsten carbide, as well as balls and beads. The instrument is also compatible with reaction vials and adapters for single-use vials, allowing for efficient processing of small sample volumes. Additionally, the MM 400 can be used with a range of material testing devices, including digital multimeters and electrical testers, to verify meter operation and ensure accurate results. These accessories and consumables make the MM 400 a highly adaptable tool for diverse laboratory applications, including asphalt mixer design and testing for quality control in construction.

Application

The Mixer Mill MM 400 is a versatile and efficient tool for grinding and homogenizing a wide range of materials, including alloys, animal feed, bones, ceramics, cereals, chemical products, coal, coke, drugs, electronic scrap, glass, grains, hair, minerals, oil seeds, ores, paper, plant materials, plastics, sewage sludge, soils, straw, tablets, textiles, tissue, tobacco, waste samples, wood, wool, and more. Its innovative design incorporates time saving features that enhance efficiency and functionality for professionals in the field. Due to its superior performance and flexibility, there are no comparable products in the market that match its features, making it an equivalent technology to other milling technologies.

Integration with Other Instruments

The Mixer Mill MM 400 can be seamlessly integrated with other instruments and devices to create a comprehensive laboratory setup. For instance, it can be used alongside a digital multimeter to measure temperature, resistance and other electrical parameters, providing a holistic approach to sample analysis. The instrument can also be connected to a computer or data acquisition system to record and analyze data in real-time. Furthermore, the MM 400 can be used in conjunction with other mixer mill models, such as the MM 500 nano and MM 500 vario, to create a flexible and scalable grinding system. This integration enables users to perform a wide range of applications, from homogenization processes to advanced cryogenic grinding and cell disruption, enhancing the overall efficiency and capability of the laboratory. For applications that require thorough mixing, consider a Blade Mixer in Dispersion for Soil designed to replace damaged mixing blades on mixers.

Features

• reproducible, fast grinding, mixing and homogenization in seconds

• powerful grinding tools by impact and friction, up to 30 Hz for up to 20 samples per run

• 3 grinding tools modes (dry, wet or cryogenic)

• screw-top grinding jars for leak-proof grinding tools

• 9 SOPs can be stored

• many accessories available: different jar and ball sizes, adapter racks for single use vials and tubes, grinding tool materials, CryoKit

• cell disruption of up to 240 ml cell suspension for DNA/RNA- and protein extraction

• auto ranging multimeter as a versatile tool for measuring various electrical parameters such as AC/DC voltage and current, resistance, and temperature

This is part of our comprehensive measurement product line designed with input from electricians for efficiency and practicality, including tools like dial thermometers that ensure accurate temperature measurement.

Safety and Maintenance

The Mixer Mill MM 400 is designed for safety and maintenance. The mill has a safety lock to prevent accidental start-up and the grinding jars have a screw-top, leak-proof design to prevent sample loss. Regular maintenance is recommended to ensure optimal performance and longevity of the mill. This includes cleaning the grinding jars and balls, checking the vibration intensity and replacing worn-out parts. The Klein Tools MM400 Multimeter is an example of electrical testers loaded with innovative features designed specifically for electricians.

Test leads are essential tools for effectively utilizing the multimeters for various functions like voltage and current measurement.

Troubleshooting and Support

In case of any issues or problems with the Mixer Mill MM 400, users can refer to the user manual or contact the manufacturer’s support team for assistance. The instrument is designed with a low battery indicator and warnings attached to ensure safe operation and prevent damage. Additionally, the MM 400 is constructed with materials durable materials, such as hardened steel and tungsten carbide, to withstand daily wear and tear. Regular maintenance and calibration of the instrument are also recommended to ensure optimal performance and accuracy. With its robust design and comprehensive support, the MM 400 is a reliable and trustworthy instrument for laboratories and labs, ensuring consistent and accurate results.

Order Information

The RETSCH Mixer Mill MM 400 can be ordered on our website or by contacting our customer service. Please note that the mill is available with different accessories: grinding jars, grinding balls, adapter racks for cell and tissue disruption. The Klein Tools MM400 Multimeter is a versatile instrument for measuring various electrical parameters, designed specifically for electricians. It also has the ability to measure test diodes alongside other electrical parameters such as voltage, current and resistance.